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What’s in the Book?
The culmination of over 25 years' expertise in nucleic acid chemistry.
Includes comprehensive background information and literature citations, detailed application information, and extensive protocols and physical data for everyday use.
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GUIDEBOOK FOR THE SYNTHESIS OF OLIGONUCLEOTIDES
This 192-page guide will tell you everything you need to know about oligo synthesis & applications.
"My research group is concerned with developing RNA aptamers against various biological targets, and so in my role, keeping up to date with the latest advancements in nucleic acid modifications and reagents is vital. For me, the LINK Guidebook is extremely useful – especially the protocols section - but the handy working examples and further external referencing are also an easy port-of-call when I’m required to synthesize new oligos.”
Amy Barker, Research Technician, University of Leeds
DON'T JUST TAKE OUR WORD FOR IT...
Chemistry of Oligonucleotide Synthesis
Oligonucleotide Synthesis Cycle
Choosing a Solid Support
Protection Group Strategies
Modifiers and Their Use in Oligonucleotide Synthesis
Colourimetric Detection & Capture
Using Photocleavable (PC) Modifiers
Modifications for Nuclease Resistance
Applications of Modified Oligonucleotides
Oligonucleotide Synthesis & Bioconjuation Protocols
Cell Delivery and Uptake